The Mavericks opened up with a pair of three’s by freshman Alli Hoeffer and sophomore Ali Wilkinson en route to an 8-2 lead in the game’s first four minutes.
Midway through the first half, MSU held a 19-11 lead over the Peacocks and opened its lead into double-digits as it opened a 42-22 lead at the break.
The Mavericks shot 41.7 percent from the floor in the first half, while limiting UIU to just 33 percent.
The 22-point halftime advantage was the largest lead the Mavericks have had since playing Dakota State in November.
Minnesota State sophomore Stephanie Haight finished the half with nine points and six rebounds, with Wilkinson matching the six rebounds and adding eight points of her own in the half. Haight came off the bench and finished with a career-high 15 points and Wilkinson also tallied 15 points of her own.
The Mavericks did not let up in the second half as the continued to roll thanks to sharp shooting and aggressive defense.
Wilkinson started a 9-0 run that lasted six minutes and 25 seconds that gave Minnesota State a 55-26 cushion.
Senior guard Andrea Walsh set a new career-high of five steals against UIU, as Hoeffer would finish with a career-high of 10 points.
MSU finished shooting 24-of-70, 51 rebounds and 12 steals as they triumphed past the Peacocks.
Minnesota State (5-4, 2-3 NSIC) is set to play at Winona State Saturday with the tipoff slated for 5 p.m.